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The FDA announced the approval of a new weight-loss drug on Sept. 11, 2014. The drug name is Contrave.

Using two separate drugs to lose weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with fat loss and the those who go through it you need to err to the side of caution and permit the FDA do its job and demand some study be done so the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say everything to keep people on his or her medications.

Researchers discovered that participants investing in this drug for any year, dropped excess weight within four weeks and have kept the body weight off through the 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more potent and safer.

Combo-pilling may be the newest fad or even better the newest ahead under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that since right now there are not any long term prescription weightloss pills that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise blood pressure and heart rate, and must not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high hypertension, as well as by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

Suboxone consists of two drugs; buprenorphine and naloxone. The naloxone is irrelevant when the addict uses the medication properly, but if the tablet is dissolved in water and injected the naloxone may cause instant withdrawal. When suboxone is employed correctly, the naloxone is destroyed within the liver right after uptake from the intestines and it has no therapeutic effect. Buprenorphine may be the active substance; it is absorbed within the tongue (and during the entire mouth) but destroyed from the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I manipulate this formulation when the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I in addition have treated addicts who have had gastric bypass, the place that the first the main intestine is bypassed and the stomach contents empty into a more distal area of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy the location where the drug is taken up from the duodenum and transferred straight away to the liver with the portal vein, where it's quickly and completely destroyed. After gastric bypass naloxone can be taken on by areas of the intestine which aren't served by the portal system, causing blood levels of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.